CCNE2 and neoplasm: Our data indicate that uc.339 is directly silenced by TP53 (Fig. 9) and that uc.339 sequesters miR-339, -663b, and -95 (Figs. 5 and 6) leading to upregulation of CCNE2 (Fig. 7) and increased tumor growth and migration both in vitro and in vivo (Figs. 2 and 3).