NOS3 and atrial fibrillation: After vigorous intensity over 19 h, among NOS3 variants passing multiple testing thresholds, as the #MA increased in rs891512 (P = 6.4E‐04), rs867225 (P = 6.5E‐04), rs743507 (P = 2.6E‐06), and rs41483644 (P = 2.4E‐04), systolic (SBP) decreased from 17.5 to 33.7 mmHg; and in rs891512 (P = 9.7E‐05), rs867225 (P = 2.6E‐05), rs41483644 (P = 1.6E‐03), rs3730009 (P = 2.6E‐04), and rs77325852 (P = 5.6E‐04), diastolic BP decreased from 11.1 mmHg to 20.3 mmHg among AF only.