Because of its documented role in the etiology of hypertension and regulation of exercise performance, we completed several studies investigating the influence of the endothelial nitric oxide synthase (NOS3) single‐nucleotide variant (SNV) ‐786 T>C (rs2070744) on PEH at varying exercise intensities among 50 Caucasian men with pre‐ to Stage 1 hypertension (Augeri et al. The gene discussed is NOS3; the disease is Hypertension.