LDLR and hyperlipidemia: We incubated primary ECs obtained from C57BL/6J (C57-ECs, normolipidemia) mice containing LDLR and LDb (LDb-ECs, hyperlipidemia) mice not containing LDLR with LDb-LDL from LDb mice (20 μg/well), LTp-LDL from LTp mice (20 μg/well), or PBS (control untreated) for 24 h.