While SEMA3A has not been described to be associated with human psychiatric disorders so far, the 16p13.11 deletion has previously been found to be associated with OCD [24] and with a variety of neurodevelopmental disorders, such as ASD, ID, epilepsy, and schizophrenia [46, 47], with reduced and male-biased penetrance [48]. This evidence concerns the gene SEMA3A and psychiatric disorder.