As a first step toward understanding whether HDAC6 is involved in the regulation of peritoneal fibrosis, we examined the effect of TA, a highly selective inhibitor of HDAC6 [34], on the EMT ofcultured human peritoneal mesothelial cells (HPMCs) in response to TGF-β1. The gene discussed is TGFB1; the disease is Peritoneal Fibrosis.