Herein, we show endometrial express LPA receptors LPA1–5, while LPA6 was undetectable in the endometria of both patients with adenomyosis and healthy controls (data of LPA6 not shown).As shown in Fig. 1, In endometrium in healthy control group, LPA1, LPA4 and LPA5 staining were little in both stroma and epithelial cells, LPA2 and LPA3 staining were localized to the nuclei of both stromal and glandular cells. This evidence concerns the gene LPAR2 and adenomyosis.