2008), CEP290 and GUCY2D were the most predominant causes of LCA, representing over one‐third of this group. At the time of analysis, three pedigrees (10%) remain unresolved, with NMNAT1 (identified in three pedigrees), AIPL1, CRB1, RPE65, RPGRIP1, TULP1, LCA5, RDH12, and SPATA7 accounting for the remaining pedigrees. This evidence concerns the gene LCA5 and Leber congenital amaurosis.