The combination of the PLT count (< 15.3 × 104/μL), albumin concentration (< 4.0 g/dL), and AAR (> 0.9; i.e., the PLALA score) is a good predictor of cirrhosis in patients with NAFLD based on data from the Japan Study Group of NAFLD (JSG-NAFLD) group [42]. The gene discussed is ALB; the disease is Cirrhosis.