GRIN1 and Sepsis: Savignac et al. found that a single injection of 0.75 mg/kg LPS decreased GluN2B levels in the frontal cortex at 28 h after LPS, but the treatment had no obvious effect on the levels of GluN1 or GluN2A[16].These data suggest that NMDA receptors could be the molecular targets of sepsis damage and that they may be involved in sepsis-related brain dysfunction in septic survivors.