AFP and Cirrhosis: By multivariate analyses, independent predictors of RFS were female sex (HR = 0.197, p = 0.024), BMI >27.5 kg/m2 (hazard ratio (HR) = 1.882, p = 0.012), BCLC stage B-C (HR = 1.573, p = 0.046), serum AFP level >20 ng/mL (HR = 2.082, p = 0.001) and histological cirrhosis (HR = 2.257, p<0.001).