No significant correlations were found for rs7763881, rs6983267 genotypes, serum HULC and CCAT2 with tumor-related data, nodal and distant metastases, except a negative correlation between rs7763881 AC genotype and the presence of mucinous adenocarcinoma (adjusted OR = 0.152, 95% CI = 0.035–0.666, P = 0.016) after adjustment for age and sex. Here, CCAT2 is linked to colon mucinous adenocarcinoma.