Elevation in the serum C-reactive protein (CRP) level, anemia (hemoglobin < 12 g/dL) and thrombocytopenia (platelet < 140 k/μL) were observed in 70.6%, 39.7% and 12.9% of patients, respectively, in the NTM-PI group. The gene discussed is CRP; the disease is anemia (phenotype).