DSP and arrhythmogenic cardiomyopathy with wooly hair and keratoderma: Mutations in junctional plakoglobin (JUP) and desmoplakin (DSP) cause Naxos disease and Carvajal syndrome respectively, two cardiocutaneous syndromes that include symptoms of woolly hair, cardiomyopathy, and palmoplantar keratoderma9.