MAPK1 and melanoma: The baseline MAPK model (Melanoma ERK Model in INDRA; MEMI1.0) consists of 14 sentences describing canonical reactions involved in ERK activation by growth factors (Fig 6B, MEMI1.0) and corresponds in scope to previously described models of MAPK signaling (Birtwistle et al, 2007; Stites et al, 2007).