These polymorphisms may lead to lower AKT1 protein levels in schizophrenia (Emamian et al., 2004; van Beveren et al., 2012), although increased AKT1 expression and activity also have been reported in schizophrenia (Hino et al., 2016; Kumarasinghe et al., 2013). The gene discussed is AKT1; the disease is schizophrenia.