As shown in Figure 2, the IL‐4 levels in response to native‐AgB (Figure 2A), as demonstrated,12 and to the AgB total pool (Figure 2C) were significantly associated with CE (P < .0001 and P = .005, respectively) in all the subjects enrolled (40 patients with CE and 26 NO‐CE subjects). This evidence concerns the gene IL4 and cholesteryl ester measurement.