The BAZ proteins (Bromodomain Adjacent to Zinc finger) represents a diverse set of proteins including BAZ1A, BAZ1B, BAZ2A and BAZ2B.109 Both BAZ2A and BAZ2B have been shown to be involved in chromatin remodelling110 and regulation of non-coding RNAs.111 Mutations in the BAZ2B gene has been linked to sudden cardiac death112 and over expression of BAZ2B negatively affects the outcome of pediatric B cell acute lymphoblastic leukemia (B-ALL).113. The gene discussed is BAZ2B; the disease is precursor B-cell acute lymphoblastic leukemia.