EWSR1 and amyotrophic lateral sclerosis: This includes EWSR1, HNRNPA3, HNRNPU, and HNRNPUL1. Except for being previously identified as a known ALS gene, EWSR1 is not distinct from the other RRM-containing proteins with a PrLD under consideration; therefore EWSR1 is included in the analysis of synergy detailed above.