EEF1G and amyotrophic lateral sclerosis: Within this cohort we identified an additional example of an ALS patient carrying a p.D403E mutation in EEF1G, a p.P12R mutation in HNRNPA3, and a p.A297P/p.A308P mutation in SRPK2. This clustering of cases for each of these genes supports the functional significance of the rare variants we have discovered.