Lp-PLA2 was also associated with risk of ACS in young patients when adjusted for traditional risk factors, including age, sex, DM, hypertension, smoking, TC, LDL-C, TG and hs-CRP (OR = 1.98, 95%CI = 1.10–3.56, P = 0.023). The gene discussed is PLA2G7; the disease is hypertensive disorder.