The CKDGen data43,44 weakly supported an association between the TMC6–TMC8 locus and the urinary albumin-to-creatinine ratio (UACR) in nondiabetic subjects (P = 0.030) but did not support an association with the chronic kidney disease (CKD) risk (P = 0.92), eGFRcrea (P = 0.39), eGFRcys (P = 0.72), and microalbuminuria (MA; P = 0.81) (Supplementary Tables S8 and S9). Here, ALB is linked to chronic kidney disease.