CCR2 and neoplasm: The potential importance of CCR2-expressing cells in radiation therapy is also observed in the Lewis Lung Carcinoma (LLC) tumor model, where LLC tumors grown in CCR2−/− hosts showed significant regression post-IR compared to LLC grown in WT mice (Fig. 2b, CCR2−/− IR 228 ± 166 vs. WT IR 1300 ± 199, day 24, P < 0.01: Student’s t-test).