Although no studies of this kind have yet been reported using iPSCs from patients with BD, Birey et al.[102] reported that, intriguingly, spheroids made with iPSCs from patients with Timothy syndrome (caused by a gain-of-function coding CACNA1C mutation) exhibited interneuron migratory abnormalities that could be normalised by a VGCC antagonist. This evidence concerns the gene CACNA1C and Behcet disease.