MALAT1 and hepatocellular carcinoma: For example, HULC, MALAT1, UCA1, and DBH-AS1 were upregulated in HBV-related HCC tissues and HBx-expressing hepatic cell lines, and their expression as positively correlated with those of HBx in HBV-related HCC tissues [11,12,13,18]; HOTAIR was also increased in HBV-related HCC and live tumors of X/c-myc transgenic mice [14].