In the context of leukemia, T‐ALL blasts with a reduced glutamine dependence are suggested to undergo a metabolic switch toward glucose metabolism.37 Arginine supplementation can also induce indirect changes in glucose regulation via insulin‐induced phosphorylation of Akt in muscle and adipose tissue of diabetic rats.38 Thus, these glycolytic changes likely derive from non‐leukemic tissues. Here, AKT1 is linked to acute lymphoblastic leukemia.