For patients on intensive insulin therapy (1 or 2 daily injections of basal insulin+3 injections of shortly acting insulin alongside main meals), who during the past 6 months, despite changes in therapy scheme, fail to achieve satisfactory glucoregulation (HbA1c <6.5%), who have more than one hypoglycemia episode weekly, and who fail to achieve glycemia control with other types of insulin. Here, INS is linked to Hypoglycemia.