NLRP3 and mantle cell lymphoma: This was supported by additional data from the same study, using skin biopsies and PBMCs from CL patients infected with L. braziliensis, which IL-1β was highly expressed in skin lesions and blockade of the Nlrp3 inflammasome prevented the IL-1-β secretion from skin biopsies, suggesting a similar pathogenic mechanism might be operating during clinical MCL.