(2) Obesity-related➀Decrease body and visceral adipose weights, and reduce lipid and blood glucose levels,➁Increase Fiaf gene expression, and decreasesLPL, SCD1, PPAR-γ, ACC1, Fas mRNA expression correlation with fatty acids synthesis, lipogenesis and adipogenesis. The gene discussed is FAS; the disease is obesity due to melanocortin 4 receptor deficiency.