To this end we performed proliferation assays with apoptosis-resistant BCL2 overexpressing MYC-transgenic mouse B cells (Fig. 7a), pre-B ALL cells lacking BAX/BAK (Fig. 7b), as well as BCL2 overexpressing Burkitt lymphoma cell lines (Fig. 7c). The gene discussed is BCL2; the disease is acute lymphoblastic leukemia.