To understand the role of BRD4 in transcriptional regulation of tumor-induced skeletal muscle wasting, we mapped the genome-wide distribution of BRD4 in skeletal muscles from control and C26-tumor-bearing mice treated with either (−)-JQ1 (20 mg/kg/day) or (+)-JQ1 (20 mg/kg/day) by ChIP-seq. The gene discussed is BRD4; the disease is neoplasm.