In addition, (+)-JQ1 administration did not impact c-Myc protein levels21, Caspase-3 activation23 (Fig. 1d) phosphorylated histone H324 (Supplementary Fig. 1), suggesting that C26 adenocarcinoma cells proliferation and apoptosis were not influenced by (+)-JQ1 administration. This evidence concerns the gene MYC and adenocarcinoma.