To characterize the HIV-specific CD8+ T-cell responses associated with HLA-B*27:02 and immune control of HIV infection, we tested in gamma interfereon (IFN-γ) enzyme-linked immunosorbent spot (ELISpot) assays recognition of a panel of 410 overlapping peptides spanning the B clade proteome (14). The gene discussed is HLA-B; the disease is HIV infectious disease.