LRRK2 and Parkinson disease: According to our cohort, different than in males, in females there is no predictive value of exosome pS1292-LRRK2 levels in PD diagnosis, potentially owing to the overall lower LRRK2 levels in females versus males and overall positive correlation of pS1292-LRRK2 to total LRRK2 protein in all subjects [8].