FMO5 and Obesity: Considering that hypoxia can increase reactive oxygen species (ROS) generation in ASCs by a nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-dependent mechanism [23, 24] and that the disproportionate increase in ROS could affect the functions of ASCs [25], we evaluated the expression levels of several members of the NADPH oxidase family due to their involvement in the redox imbalance that occurs in adipose tissue during obesity [26].