An increase in transcript expression was observed at 15°C for all B cell markers studied (secretory igm, membrane-bound igt, pax5, and blimp1) in the anterior kidney post-infection with Tetracapsuloides bryosalmonae, and for all but IgT in the posterior kidney, with blimp1, the B cell differentiation marker being most strongly up-regulated [34]. This evidence concerns the gene PRDM1 and infection.