Nevertheless, in contrast to past findings, we found that the CYP1A2 AA, CA, and CA + AA genotypes were associated with an increased risk of prostate cancer (Table 4) and that the CYP1A2 CA + AA genotype (OR, 4.01; 95% CI, 1.60–10.05; P for interaction, 0.003) was higher than the CC genotype (OR, 2.65; 95% CI, 0.97–7.29) among individuals with high HAA intake, even though the CC genotype OR is not statistically significant, we still can find the trend (Table 5). Here, CYP1A2 is linked to Familial prostate cancer.