Between the EWASs reviewed, we observed an overlap for a number of CpGs (TXNIP, ABCG1, SOCS3, SREBF1 and CPT1A) from EWASs performed in blood samples from Europeans, Indian Asians, Mexican Americans and Arabs, suggesting an association of DNA methylation with type 2 diabetes at these sites, irrespective of ethnic, social and environmental differences. This evidence concerns the gene SOCS3 and type 2 diabetes mellitus.