EGFR and non-small cell lung carcinoma: And the preliminary data presented at American Society of Clinical Oncology (ASCO) 2017 from a phase III ARCHER 1050 study (NCT01774721) also demonstrated dacomitinib was superior to gefitinib as the first-line treatment of NSCLC patients with mutant EGFR (PFS, 14.7 vs. 9.2 months; HR 0.59, 95% CI 0.47–0.74; p < 0.0001) [20].