As shown in Supplementary Figure 1, the AUC values of DCP, AFP, and DCP + AFP in distinguishing between HCC (G 1) and liver cirrhosis (G 2) were 0.860 (95% CI: 0.770–0.925, sensitivity [Se]: 0.76, specificity [Sp]: 0.86), 0.805 (95% CI: 0.707–0.882, Se: 0.73, Sp: 0.84), and 0.859 (95% CI: 0.768–0.924, Se: 0.84, Sp: 0.77), respectively. The gene discussed is AFP; the disease is cirrhosis of liver.