MMP2 and cancer: Because it might increase cancer invasion by inducing MMP synthesis in neighboring fibroblasts, endothelial and cancer cells, including MT-MMP, MMP-1, MMP-2, and MMP-3, and the endogenous activators of MMP-2, CD147 is also named as EMMPRIN, which indicates its Extracellular Matrix Metalloproteinase Inducer activity [1–2].