SLC39A4 and neoplasm: Our data presented here confirmed ZIP4 over-expression in EOC tissues (Supplementary Figures 1-2) and support an innovative hypothesis that the apparent disconnection between Zn and ZIP4's effects in EOC (as mentioned in the Introduction) is due to, at least in part, the fact that ZIP4 is able to mediate LPA's tumor promoting activity in an extracellular Zn-independent manner.