The results showed that, as compared the marginal normal lung cells, the expression of Fas was lower (Figure 1A-1B) in LCCs, the levels of p53 was not different between the normal group and the LC group (Figure 1C, and the PAR2 expression was higher in LCCs (Figure 1D-1E). This evidence concerns the gene FAS and laryngotracheoesophageal cleft.