Among a sample of 603 patients with stage II-IV high-grade serous ovarian cancer obtained from The Cancer Genome Atlas (TCGA) database [22, 23], higher expression of PAI-1 mRNA was associated with significantly shorter PFS (median PFS: 13.0 vs. 15.4 months, P = 0.015, Figure 1H) as well as OS (median OS: 27.6 vs. 34.9 months, P = 0.031; Figure 1I). Here, SERPINE1 is linked to ovarian serous adenocarcinoma.