AXL and neoplasm: In addition, recent studies have demonstrated that anti-Axl therapeutics, such as Axl-specific antibodies, are able to inhibit tumor growth and metastasis and enhance the therapeutic effect of multiple anticancer therapies (including anti-angiogenesis therapy, targeted therapy and chemotherapy) in the transplantable tumor models or patient-derived xenograft (PDX) models [37–39], indicating a translational potential of combinatorial therapeutics of anti-Axl antibodies and other conventional treatments.