Here we focussed on NF-κB-driven cFLIP expression because it is common in many cancers [21, 38] Indeed, the NF-κB inhibitor, EF24 elicited cFLIP downregulation in primary thymoma TECs and 1889 thymic carcinoma cells [13] (Figure 4A and Supplementary Figure 6A) and sensitized them to TNFα induced cell death (Figure 4B and 4C and Supplementary Figure 6B and 6C). This evidence concerns the gene NFKB1 and thymoma.