CD8A and systemic lupus erythematosus: To further determine which population of thymic CD4-CD8+ T cells was regulated by thymic B cells in lupus-prone mice, we first identified CD4-CD8+ T cell phenotype by analyzing CD3, RORγt, and CD24 expression in C57BL/6 (Figure 4A and 4B) and MRL/+ (Supplementary Figure S4A and S4B) mice.