Guar et al. found that 915G/C SNP did not show any significant difference in genotype and allele frequencies between patients and controls (Gaur et al., 2011), while Hsu et al. concluded that the C allele and the GC genotype of TGF-β1 was significantly higher in frequency in cancer patients compared with a healthy control group (Hsu et al., 2015). This evidence concerns the gene TGFB1 and cancer.