Therefore, miR-30a-5p silencing induced by its antagomir abrogated the anti-inflammatory activity of emodin in pancreatitis rats, which showed that miR-30a-5p exerted critical regulation in anti-inflammatory effect of emodin by regulating HTRA1/TGFβ1 signaling pathway. This evidence concerns the gene TGFB1 and pancreatitis.