The analysis of peripheral lymphoid organs and tumor tissue revealed (i) localization of CD1d-antitumor proteins at the tumor site, (ii) recruitment of iNKT, NK, and T cells at the tumor, (iii) sustained activation of iNKT cells, and (iv) adjuvant effect on CD8 T cell priming (as depicted in the Figure 1). Here, CD1D is linked to neoplasm.