The percentage of PD-L1+ cells in CD4+ and CD8+ TIL was positively correlated with tumor size, IHC scores for %stromal TIL, %global TIL, %intratumoral TIL, and %CD8+, even if only a low proportion of PD-L1+ TIL was detected (Figure 2B; Table S5 in Supplementary Material). The gene discussed is CD274; the disease is neoplasm.