No or reduced TACI membrane expressionImpaired NF-κB signalingImpaired IgA and IgG class switchingReduced response to TI-2 AgsB-cell lymphoproliferations, splenomegalyIncreased frequency of autoimmune diseasesLack of lupus-like symptoms. This evidence concerns the gene TNFRSF13B and systemic lupus erythematosus.