In particular, thyroid tissues from HT patients without vitiligo, and normal thyroid tissues, were both negative for the expression of NKI/beteb, Pmel17, TRP-1, HMB-45, and S100, whereas they were positive for the expression of TRP-2, lysosome-associated membrane protein 1 (LAMP1), and CD69. This evidence concerns the gene PMEL and vitiligo.